Marco Oppedisano (born November 20, 1971 in Brooklyn, New York) is an American guitarist and composer whose compositions focus on the innovative use of electric guitar in the genre of electroacoustic music. His musique concrete/acousmatic compositions have utilized multitrack recording and extended performance techniques for electric guitar and bass. In addition to musique concrete, compositions by Oppedisano also consist of "live" electric guitar in combination with a fixed playback of various electronic, acoustic (specifically female voice courtesy of Kimberly Fiedelman) and sampled sounds.

Oppedisano has also composed works for solo classical guitar, solo electric guitar and mixed ensemble.

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